Cylinder number and arrangement depends on the purpose of the engine. Smaller (four and six cylinder) engines in front-wheel drive vehicles often use an inline design which orients cylinders vertically over the crankshaft and aligns them in a row. Other common orientations are a horizontal/opposed design which places cylinders flat facing each other with the crankshaft between them and a V-type design common in six and eight cylinder engines that features one cylinder head per block of cylinders oriented at a 60 to 90 degree angle to each other with the crankshaft at the bottom of the V.

The stroke cycle of an engine is governed by the crankshaft which serves to regulate the firing order of the cylinders. All cylinders are not on the same stroke at the same time and correct firing order is important to balance engine operation and minimize vibrations. A common firing order for four-cylinder engines is 1-3-4-2 which indicates that cylinders 1 and 3 fire (power stroke)together and cylinders 4 and 2 fire together.

Combustion is the burning of an air-fuel mixture to provide energy. It requires the presence of air, fuel, and a heat source to ignite the air-fuel mixture. In the internal combustion engine that powers automobiles and trucks the combustion happens inside the engine utilzing a fuel like gasoline, diesel fuel, or natural gas.

A differential is designed to drive a pair of wheels while allowing them to rotate at different speeds. A transaxle is a transmission that incorporates the differential in one package. Most front-wheel drive cars use a transaxle while rear-wheel drive cars use a transmission and separate differential connected via a drive shaft. The differential is incorporated into the drive axle which splits engine power delivered by the drive shaft between the two drive wheels. All-wheel drive cars typically use a transaxle that includes an output shaft to the rear differential.

The transmission provides the appropriate power to vehicle wheels to maintain a given speed. The engine and the transmission have to be disconnected to shift gears and a manual transmission requires the driver to manually manage this disconnection (using a clutch) and to manually shift gears. An automatic transmission is essentially an automatic gear shifter and handles this process without driver input.