Modern car engines are cooled by liquid which circulates through the engine block and cylinder heads absorbing excess heat. This liquid is made up of half water and half antifreeze (commonly, ethylene glycol) which both keeps the water from freezing at low temperatures and raises its boiling point making heat transfer more efficient.

Cylinder number and arrangement depends on the purpose of the engine. Smaller (four and six cylinder) engines in front-wheel drive vehicles often use an inline design which orients cylinders vertically over the crankshaft and aligns them in a row. Other common orientations are a horizontal/opposed design which places cylinders flat facing each other with the crankshaft between them and a V-type design common in six and eight cylinder engines that features one cylinder head per block of cylinders oriented at a 60 to 90 degree angle to each other with the crankshaft at the bottom of the V.

Most modern cars use an independent suspension system on the front wheels. This setup allows each of the wheels on an axle to move independently in response to road level variations. Independent suspension offers much better handling and stability when compared to a rigid axle suspension at the cost of being structurally weaker and more costly to maintain.

A differential is designed to drive a pair of wheels while allowing them to rotate at different speeds. A transaxle is a transmission that incorporates the differential in one package. Most front-wheel drive cars use a transaxle while rear-wheel drive cars use a transmission and separate differential connected via a drive shaft. The differential is incorporated into the drive axle which splits engine power delivered by the drive shaft between the two drive wheels. All-wheel drive cars typically use a transaxle that includes an output shaft to the rear differential.