The aorta is the body's largest artery and receives blood from the pulmonary vein via the left ventricle. From there, blood is circulated through the rest of the body through smaller arteries called arterioles that branch out from the heart. Finally, blood is delivered to bodily tissues through capillaries.

To provide oxygen to the body, blood flows through the heart in a path formed by the right atrium → right ventricle → lungs → left atrium → left ventricle → body. When blood enters the right side of the heart it is deoxygenated. It enters the left side of the heart oxygenated after traveling to the lungs.

The heart is the organ that drives the circulatory system. In humans, it consists of four chambers with two that collect blood called atria and two that pump blood called ventricles. The heart's valves prevent blood pumped out of the ventricles from flowing back into the heart.