The biosphere is the global ecological system integrating all living beings and their relationships. This includes their interactions with the lithosphere (the rigid outer part of the earth, consisting of the crust and upper mantle), hydrosphere (all surface water), and atmosphere (the envelope of gases surrounding the planet).

The nucleus of a eukaryotic cell contains the genetic material of the cell and is surrounded by cytoplasm which contains many organelles. These include:

In contrast to the Celsius scale (measured in degrees centigrade) that fixes 0° at the freezing point of water and the Fahrenheit scale that uses 32°, the Kelvin scale fixes 0° at absolute zero (-273°C) which is the lowest temperature possible in the universe.

Part of the brainstem, the medulla is the connection between the brain and the spinal cord. It controls involuntary actions like breathing, swallowing, and heartbeat.

In the mesosphere, temperature again drops as altitude increases until the coldest point in the Earth's atmosphere, the mesopause, is reached where temperatures fall to −225 °F (−143 °C).