The biosphere is the global ecological system integrating all living beings and their relationships. This includes their interactions with the lithosphere (the rigid outer part of the earth, consisting of the crust and upper mantle), hydrosphere (all surface water), and atmosphere (the envelope of gases surrounding the planet).

Blood transfer is limited by the type and Rh factor of the blood. Someone who has Rh-factor negative blood cannot receive blood with a positive type but a person with Rh-factor positive type blood can receive Rh-negative blood. Type O negative blood is the universal donor because it can be given to a person with any blood type. Type AB positive is the universal recipient meaning someone with this blood type can receive any other type of blood.

Some plant cells produce their own energy through photosynthesis which is the process by which sunlight, carbon dioxide, and water react to make sugar and oxygen. Animal cells cannot produce their own energy and, instead, generate energy when mitochondria consume outside sugar and oxygen through aerobic respiration.

The crust is the Earth's outermost layer and is divided into oceanic and continental types. Oceanic crust is 3 miles (5 km) to 6 miles (10 km) thick and is composed primarily of denser rock. Continental crust is 20 to 30 miles (30 to 50 km) thick and composed primarily of less dense rock. The crust makes up approximately one percent of the Earth's total volume.

If no oxygen is present, cellular respiration is anaerobic and will result in fermentation where either lactic acid or alcohol is used instead of oxygen.