Blood transfer is limited by the type and Rh factor of the blood. Someone who has Rh-factor negative blood cannot receive blood with a positive type but a person with Rh-factor positive type blood can receive Rh-negative blood. Type O negative blood is the universal donor because it can be given to a person with any blood type. Type AB positive is the universal recipient meaning someone with this blood type can receive any other type of blood.

In the mesosphere, temperature again drops as altitude increases until the coldest point in the Earth's atmosphere, the mesopause, is reached where temperatures fall to −225 °F (−143 °C).

Newton's second law of motion states that The acceleration of an object as produced by a net force is directly proportional to the magnitude of the net force, in the same direction as the net force, and inversely proportional to the mass of the object. This law basically means that the greater the mass of an object, the more force is needed to overcome its inertia.

Temperatures again increase with altitude in the thermosphere which is the hottest (4,530 °F / 2,500 °C) atmospheric layer due to direct exposure to the Sun's radiation. However, the gas in this layer is highly diluted so even though the atoms of gas may be very high in temperature, there are too few of them to effectively transfer much heat.

Veins carry blood back to the heart from the body. While arteries are thick-walled because they carry oxygenated blood at high pressure, veins are comparatively thin-walled as they carry low-pressure deoxygenated blood. Like the heart, veins contain valves to prevent blood backflow.