To provide oxygen to the body, blood flows through the heart in a path formed by the right atrium → right ventricle → lungs → left atrium → left ventricle → body. When blood enters the right side of the heart it is deoxygenated. It enters the left side of the heart oxygenated after traveling to the lungs.

Blood transfer is limited by the type and Rh factor of the blood. Someone who has Rh-factor negative blood cannot receive blood with a positive type but a person with Rh-factor positive type blood can receive Rh-negative blood. Type O negative blood is the universal donor because it can be given to a person with any blood type. Type AB positive is the universal recipient meaning someone with this blood type can receive any other type of blood.

Like the respiratory system, the circulatory system serves to transport oxygen throughout the body while removing carbon dioxide. In addition, the circulatory system transports nutrients from the digestive system.

Food is mixed with gastric acid and pepsin in the stomach to help break down protein.

Temperatures again increase with altitude in the thermosphere which is the hottest (4,530 °F / 2,500 °C) atmospheric layer due to direct exposure to the Sun's radiation. However, the gas in this layer is highly diluted so even though the atoms of gas may be very high in temperature, there are too few of them to effectively transfer much heat.