The biosphere is the global ecological system integrating all living beings and their relationships. This includes their interactions with the lithosphere (the rigid outer part of the earth, consisting of the crust and upper mantle), hydrosphere (all surface water), and atmosphere (the envelope of gases surrounding the planet).

Blood transfer is limited by the type and Rh factor of the blood. Someone who has Rh-factor negative blood cannot receive blood with a positive type but a person with Rh-factor positive type blood can receive Rh-negative blood. Type O negative blood is the universal donor because it can be given to a person with any blood type. Type AB positive is the universal recipient meaning someone with this blood type can receive any other type of blood.

An endoskeleton (internal skeleton) is a charateristic of vertebrate animals, including humans.

The Earth is approximately 4.6 billion years old and its history is divided into time periods based on the events that took place and the forms of life that were dominant during those periods. The largest graduation of time is the eon and each eon is subdivided into eras, eras into periods, periods into epochs, and epochs into ages.

Mantle makes up 84% of the Earth's volume and has an average thickness of approximately 1,800 miles (2,900 km). It is dense, hot, and primarily solid although in places it behaves more like a viscous fluid as the plates of the upper mantle and crust gradually "float" along its circumference.