The broadest classification of life splits all organisms into three groups called domains. The three domains of life are bacteria, archaea and eukaryota.

The heart is the organ that drives the circulatory system. In humans, it consists of four chambers with two that collect blood called atria and two that pump blood called ventricles. The heart's valves prevent blood pumped out of the ventricles from flowing back into the heart.

In the mesosphere, temperature again drops as altitude increases until the coldest point in the Earth's atmosphere, the mesopause, is reached where temperatures fall to −225 °F (−143 °C).

Digestion begins in the mouth where the teeth and tongue break down food mechanically through chewing and saliva, via the enzyme salivary amylase, starts to break starches down chemically. From the mouth, food travels down the esophagus where contractions push the food into the stomach.

Veins carry blood back to the heart from the body. While arteries are thick-walled because they carry oxygenated blood at high pressure, veins are comparatively thin-walled as they carry low-pressure deoxygenated blood. Like the heart, veins contain valves to prevent blood backflow.