The biosphere is the global ecological system integrating all living beings and their relationships. This includes their interactions with the lithosphere (the rigid outer part of the earth, consisting of the crust and upper mantle), hydrosphere (all surface water), and atmosphere (the envelope of gases surrounding the planet).

Blood transfer is limited by the type and Rh factor of the blood. Someone who has Rh-factor negative blood cannot receive blood with a positive type but a person with Rh-factor positive type blood can receive Rh-negative blood. Type O negative blood is the universal donor because it can be given to a person with any blood type. Type AB positive is the universal recipient meaning someone with this blood type can receive any other type of blood.

Most animals consume other organisms to survive. Consumers (heterotrophs) are divided into three types, primary, secondary, and tertiary, based on their place in the food chain.

The heart is the organ that drives the circulatory system. In humans, it consists of four chambers with two that collect blood called atria and two that pump blood called ventricles. The heart's valves prevent blood pumped out of the ventricles from flowing back into the heart.

Tough fibrous cords of connective tissue called tendons connect muscles to the skeleton while another type of connective tissue called ligaments connect bones to other bones at joints (elbow, knee, fingers, spinal column).