The biosphere is the global ecological system integrating all living beings and their relationships. This includes their interactions with the lithosphere (the rigid outer part of the earth, consisting of the crust and upper mantle), hydrosphere (all surface water), and atmosphere (the envelope of gases surrounding the planet).

Blood is categorized into four different types (A, B, AB, and O) based on the type of antigens found on the outside of the red blood cells. Additionally, each type can be negative or positive based on whether or not the cells have an antigen called the Rh factor.

The Kuiper Belt is similar to the asteroid belt but much larger. Extending beyond the orbit of Neptune, it contains objects composed mostly of frozen methane, ammonia, and water. Most notably, the Kuiper Belt is home to Pluto, a dwarf planet that, until a 2006 reclassification, was considered the ninth planet of the solar system.

Temperatures again increase with altitude in the thermosphere which is the hottest (4,530 °F / 2,500 °C) atmospheric layer due to direct exposure to the Sun's radiation. However, the gas in this layer is highly diluted so even though the atoms of gas may be very high in temperature, there are too few of them to effectively transfer much heat.