The biosphere is the global ecological system integrating all living beings and their relationships. This includes their interactions with the lithosphere (the rigid outer part of the earth, consisting of the crust and upper mantle), hydrosphere (all surface water), and atmosphere (the envelope of gases surrounding the planet).

The carbon cycle represents the ciruit of carbon through Earth's ecosystem. Carbon dioxide (CO₂) in the atmosphere is absorbed by plants through photosynthesis. Plants then die and release carbon back into the atmosphere during decomposition or are eaten by animals who breathe (respiration) the carbon into the atmosphere they exhale and produce waste which also releases carbon as it decays.

Some plant cells produce their own energy through photosynthesis which is the process by which sunlight, carbon dioxide, and water react to make sugar and oxygen. Animal cells cannot produce their own energy and, instead, generate energy when mitochondria consume outside sugar and oxygen through aerobic respiration.

Below domain, life is classified into six kingdoms: plants, animals, archaebacteria, eubacteria, and fungi. The last kingdom, protists, include all microscopic organisms that are not bacteria, animals, plants or fungi. (Archaebacteria and eubacteria are sometimes combined into a single kingdom, monera.)

In the mesosphere, temperature again drops as altitude increases until the coldest point in the Earth's atmosphere, the mesopause, is reached where temperatures fall to −225 °F (−143 °C).