The heart is the organ that drives the circulatory system. In humans, it consists of four chambers with two that collect blood called atria and two that pump blood called ventricles. The heart's valves prevent blood pumped out of the ventricles from flowing back into the heart.

Chemical waste like excess water, minerals, and salt are filtered from the blood by the kidneys and secreted into the urine. Urine is transported from the kidneys to the bladder through ureters.

In the mesosphere, temperature again drops as altitude increases until the coldest point in the Earth's atmosphere, the mesopause, is reached where temperatures fall to −225 °F (−143 °C).

Food is mixed with gastric acid and pepsin in the stomach to help break down protein.

Tertiary consumers eat primary consumers and secondary consumers and are typically carnivorous predators. Tertiary consumers may also be omnivores. Examples include wolves, sharks, and human beings.