Hard bones provide primary support for the endoskeleton while more flexible cartilage is found at the end of all bones, at the joints, and in the nose and ears. In addition to providing support and protecting bodily organs, bones also produce blood cells and store minerals like calcium.

Capillaries are small thin-walled vessels that permit the exchange of oxygen, carbon dioxide, nutrients, and waste between blood and the body's cells. This process of exchange is called diffusion.

The nervous system consists of the brain and spinal cord (central nervous system) and the peripheral nervous system which is the network of nerve cells (neurons) that collect and distribute signals from the central nervous system throughout the body.

In the mesosphere, temperature again drops as altitude increases until the coldest point in the Earth's atmosphere, the mesopause, is reached where temperatures fall to −225 °F (−143 °C).

The two largest veins in the body, the venae cavae, pass blood to the right ventricle which pumps the blood to the lungs through the pulmonary artery. Blood picks up oxygen in the lungs and returns it to the left atrium via the pulmonary vein.