The biosphere is the global ecological system integrating all living beings and their relationships. This includes their interactions with the lithosphere (the rigid outer part of the earth, consisting of the crust and upper mantle), hydrosphere (all surface water), and atmosphere (the envelope of gases surrounding the planet).

Blood is created in bone marrow and is made up of cells suspended in liquid plasma. Red blood cells carry oxygen, white blood cells fight infection, and platelets are cell fragments that allow blood to clot.

The diaphragm is a system of muscles that allows breathing. During inhalation, the diaphragm expands and air rushes in to fill the space created. Then, during exhalation, the diaphragm contracts and forces the air back out.

The cerebrum is the major part of the brain and is responsible for the main senses (thinking, hearing, seeing).

In the mesosphere, temperature again drops as altitude increases until the coldest point in the Earth's atmosphere, the mesopause, is reached where temperatures fall to −225 °F (−143 °C).