The biosphere is the global ecological system integrating all living beings and their relationships. This includes their interactions with the lithosphere (the rigid outer part of the earth, consisting of the crust and upper mantle), hydrosphere (all surface water), and atmosphere (the envelope of gases surrounding the planet).

To provide oxygen to the body, blood flows through the heart in a path formed by the right atrium → right ventricle → lungs → left atrium → left ventricle → body. When blood enters the right side of the heart it is deoxygenated. It enters the left side of the heart oxygenated after traveling to the lungs.

Capillaries are small thin-walled vessels that permit the exchange of oxygen, carbon dioxide, nutrients, and waste between blood and the body's cells. This process of exchange is called diffusion.

The crust is the Earth's outermost layer and is divided into oceanic and continental types. Oceanic crust is 3 miles (5 km) to 6 miles (10 km) thick and is composed primarily of denser rock. Continental crust is 20 to 30 miles (30 to 50 km) thick and composed primarily of less dense rock. The crust makes up approximately one percent of the Earth's total volume.

If the ovum fails to become fertilized, the lining of the uterus sloughs off during menstruation. From puberty to menopause, this cycle of menstruation repeats monthly (except during pregnancy).