catastrophic
The definition for catastrophic is "Relating to extreme misfortune." Used in a sentence: The effects of the massive hurricane were catastrophic.
duplicity
The definition for duplicity is "Deceptive thought, speech, or action." Used in a sentence: The life of an undercover detective is filed with necessary duplicity.
insolence
The definition for insolence is "Boldness or rudeness." Used in a sentence: The boy's insolence to the policeman embarrassed his mother.
melodious
The definition for melodious is "Having a pleasing melody." Used in a sentence: The melodious sounds of the symphony soothed Tim after his trying day.
placebo
The definition for placebo is "An inactive substance used in medical testing." Used in a sentence: Tom, who had taken the placebo, found that his allergy symptoms did not go away.