The definition for demean is "To lower status." Used in a sentence: The embarrassing photograph demeaned the candidate in the eyes of the voters.

The definition for flagrant is "Noticeably offensive." Used in a sentence: The executive was fired for his flagrant abuse of the company expense account.

The definition for hedonism is "Belief that pleasure is the sole aim of life." Used in a sentence: The hedonism of the emperoro, who spent all his time giving parties, caused his downfall.

The definition for onset is "Beginning." Used in a sentence: Crocuses bloom at the onset of spring, sometimes even before the snow melts.

The definition for placebo is "An inactive substance used in medical testing." Used in a sentence: Tom, who had taken the placebo, found that his allergy symptoms did not go away.