Cylinder number and arrangement depends on the purpose of the engine. Smaller (four and six cylinder) engines in front-wheel drive vehicles often use an inline design which orients cylinders vertically over the crankshaft and aligns them in a row. Other common orientations are a horizontal/opposed design which places cylinders flat facing each other with the crankshaft between them and a V-type design common in six and eight cylinder engines that features one cylinder head per block of cylinders oriented at a 60 to 90 degree angle to each other with the crankshaft at the bottom of the V.

The combustion chamber is located in the cylinder head and contains the combustion of the air-fuel mixture. This mixture is delivered by an intake valve and the waste gases from combustion are removed from the combustion chamber by the exhaust valve.

The stoichiometric ratio defines the proper ratio of air to fuel necessary so that an engine burns all fuel with no excess air. For gasoline fuel, the stoichiometric ratio is about 14.7:1 or for every one gram of fuel, 14.7 grams of air are required. Too much air results in a lean air-fuel mixture that burns more slowly and hotter while too much fuel results in a rich mixture that burns quicker and cooler.

The four-stroke piston cycle of internal combustion engines starts with the piston at top of the cylinder head (top dead center or TDC) during the intake stroke. The piston moves downward in the cylinder creating a vacuum that pulls an air-fuel mix into the combustion chamber through the now open intake valve.

Inline cylinder arrangements number cylinders sequentially (1, 2, 3, ...) front to rear.