Cylinder number and arrangement depends on the purpose of the engine. Smaller (four and six cylinder) engines in front-wheel drive vehicles often use an inline design which orients cylinders vertically over the crankshaft and aligns them in a row. Other common orientations are a horizontal/opposed design which places cylinders flat facing each other with the crankshaft between them and a V-type design common in six and eight cylinder engines that features one cylinder head per block of cylinders oriented at a 60 to 90 degree angle to each other with the crankshaft at the bottom of the V.

The electric fuel pump feeds pressurized fuel through a fuel filter to the fuel injectors via the fuel rail manifold. The fuel rail contains the fuel pressure regulator which ensures that the fuel injectors receive fuel at a consistent and known rate. Excess fuel bled off by the pressure regulator returns to the fuel tank through the fuel return line.

Ignition timing defines the point in time at the end of the compression stroke that the spark plug fires. Measured in number of degrees before top dead center (BTDC), the exact point that the spark plugs initiate combustion varies depending on the speed of the engine. The timing is advanced (the spark plugs fire a few more degrees BTDC) when the engine is running faster and retarded when it's running slower.

Spark plugs receive current from the distributor and use it to spark combustion in the combustion chamber of a cylinder.

A differential is designed to drive a pair of wheels while allowing them to rotate at different speeds. A transaxle is a transmission that incorporates the differential in one package. Most front-wheel drive cars use a transaxle while rear-wheel drive cars use a transmission and separate differential connected via a drive shaft. The differential is incorporated into the drive axle which splits engine power delivered by the drive shaft between the two drive wheels. All-wheel drive cars typically use a transaxle that includes an output shaft to the rear differential.