The biosphere is the global ecological system integrating all living beings and their relationships. This includes their interactions with the lithosphere (the rigid outer part of the earth, consisting of the crust and upper mantle), hydrosphere (all surface water), and atmosphere (the envelope of gases surrounding the planet).

Blood transfer is limited by the type and Rh factor of the blood. Someone who has Rh-factor negative blood cannot receive blood with a positive type but a person with Rh-factor positive type blood can receive Rh-negative blood. Type O negative blood is the universal donor because it can be given to a person with any blood type. Type AB positive is the universal recipient meaning someone with this blood type can receive any other type of blood.

The nervous system consists of the brain and spinal cord (central nervous system) and the peripheral nervous system which is the network of nerve cells (neurons) that collect and distribute signals from the central nervous system throughout the body.

Newton's law of universal gravitation defines gravity: All objects in the universe attract each other with an equal force that varies directly as a product of their masses, and inversely as a square of their distance from each other. Expressed as a formula: \(\vec{F_{g}} = { Gm_{1}m_{2} \over r^2}\) where r is the distance between the two objects and G is the gravitational constant with a value of 6.67 x 10^-11.

Because different materials have different refractive indices, light changes speed when passing from one material to another. This causes the light to bend (refraction) at an angle that depends on the change in refractive index between the materials. The greater the difference, the higher the angle of refraction.