The biosphere is the global ecological system integrating all living beings and their relationships. This includes their interactions with the lithosphere (the rigid outer part of the earth, consisting of the crust and upper mantle), hydrosphere (all surface water), and atmosphere (the envelope of gases surrounding the planet).

In the mesosphere, temperature again drops as altitude increases until the coldest point in the Earth's atmosphere, the mesopause, is reached where temperatures fall to −225 °F (−143 °C).

Producers (autotrophs) serve as a food source for other organisms. Typical producers are plants that can make their own food through photosynthesis and certain bacteria that are capable of converting inorganic substances into food through chemosynthesis

The spinal cord connects the brain to the body's network of nerves. It carries impulses between all organs and the brain and controls simple reflexes.

Veins carry blood back to the heart from the body. While arteries are thick-walled because they carry oxygenated blood at high pressure, veins are comparatively thin-walled as they carry low-pressure deoxygenated blood. Like the heart, veins contain valves to prevent blood backflow.