The biosphere is the global ecological system integrating all living beings and their relationships. This includes their interactions with the lithosphere (the rigid outer part of the earth, consisting of the crust and upper mantle), hydrosphere (all surface water), and atmosphere (the envelope of gases surrounding the planet).

To provide oxygen to the body, blood flows through the heart in a path formed by the right atrium → right ventricle → lungs → left atrium → left ventricle → body. When blood enters the right side of the heart it is deoxygenated. It enters the left side of the heart oxygenated after traveling to the lungs.

Hard bones provide primary support for the endoskeleton while more flexible cartilage is found at the end of all bones, at the joints, and in the nose and ears. In addition to providing support and protecting bodily organs, bones also produce blood cells and store minerals like calcium.

The respiratory system manages respiration which is the process by which blood cells absorb oxygen and eliminate carbon dioxide.