Blood is created in bone marrow and is made up of cells suspended in liquid plasma. Red blood cells carry oxygen, white blood cells fight infection, and platelets are cell fragments that allow blood to clot.

Blood transfer is limited by the type and Rh factor of the blood. Someone who has Rh-factor negative blood cannot receive blood with a positive type but a person with Rh-factor positive type blood can receive Rh-negative blood. Type O negative blood is the universal donor because it can be given to a person with any blood type. Type AB positive is the universal recipient meaning someone with this blood type can receive any other type of blood.

The gene is the base unit of inheritance and is contained within DNA. A gene may come in several varieties (alleles) and there are a pair of alleles for every gene. If the alleles are alike, a person is homozygous for that gene. If the alleles are different, heterozygous.

The heart is the organ that drives the circulatory system. In humans, it consists of four chambers with two that collect blood called atria and two that pump blood called ventricles. The heart's valves prevent blood pumped out of the ventricles from flowing back into the heart.

In the mesosphere, temperature again drops as altitude increases until the coldest point in the Earth's atmosphere, the mesopause, is reached where temperatures fall to −225 °F (−143 °C).