The biosphere is the global ecological system integrating all living beings and their relationships. This includes their interactions with the lithosphere (the rigid outer part of the earth, consisting of the crust and upper mantle), hydrosphere (all surface water), and atmosphere (the envelope of gases surrounding the planet).

To provide oxygen to the body, blood flows through the heart in a path formed by the right atrium → right ventricle → lungs → left atrium → left ventricle → body. When blood enters the right side of the heart it is deoxygenated. It enters the left side of the heart oxygenated after traveling to the lungs.

The gene is the base unit of inheritance and is contained within DNA. A gene may come in several varieties (alleles) and there are a pair of alleles for every gene. If the alleles are alike, a person is homozygous for that gene. If the alleles are different, heterozygous.

The heart is the organ that drives the circulatory system. In humans, it consists of four chambers with two that collect blood called atria and two that pump blood called ventricles. The heart's valves prevent blood pumped out of the ventricles from flowing back into the heart.

The two largest veins in the body, the venae cavae, pass blood to the right ventricle which pumps the blood to the lungs through the pulmonary artery. Blood picks up oxygen in the lungs and returns it to the left atrium via the pulmonary vein.