The biosphere is the global ecological system integrating all living beings and their relationships. This includes their interactions with the lithosphere (the rigid outer part of the earth, consisting of the crust and upper mantle), hydrosphere (all surface water), and atmosphere (the envelope of gases surrounding the planet).

Chemical waste like excess water, minerals, and salt are filtered from the blood by the kidneys and secreted into the urine. Urine is transported from the kidneys to the bladder through ureters.

In the mesosphere, temperature again drops as altitude increases until the coldest point in the Earth's atmosphere, the mesopause, is reached where temperatures fall to −225 °F (−143 °C).

Because different materials have different refractive indices, light changes speed when passing from one material to another. This causes the light to bend (refraction) at an angle that depends on the change in refractive index between the materials. The greater the difference, the higher the angle of refraction.

Veins carry blood back to the heart from the body. While arteries are thick-walled because they carry oxygenated blood at high pressure, veins are comparatively thin-walled as they carry low-pressure deoxygenated blood. Like the heart, veins contain valves to prevent blood backflow.