Blood transfer is limited by the type and Rh factor of the blood. Someone who has Rh-factor negative blood cannot receive blood with a positive type but a person with Rh-factor positive type blood can receive Rh-negative blood. Type O negative blood is the universal donor because it can be given to a person with any blood type. Type AB positive is the universal recipient meaning someone with this blood type can receive any other type of blood.

Animal cells are surrounded by a semipermeable membrane which allows for the transfer of water and oxygen to and from the cell. In plant cells, the cell membrane is surrounded by a somewhat rigid cell wall which provides the cell structure and support.

The broadest classification of life splits all organisms into three groups called domains. The three domains of life are bacteria, archaea and eukaryota.

The heart is the organ that drives the circulatory system. In humans, it consists of four chambers with two that collect blood called atria and two that pump blood called ventricles. The heart's valves prevent blood pumped out of the ventricles from flowing back into the heart.