The biosphere is the global ecological system integrating all living beings and their relationships. This includes their interactions with the lithosphere (the rigid outer part of the earth, consisting of the crust and upper mantle), hydrosphere (all surface water), and atmosphere (the envelope of gases surrounding the planet).

Blood is categorized into four different types (A, B, AB, and O) based on the type of antigens found on the outside of the red blood cells. Additionally, each type can be negative or positive based on whether or not the cells have an antigen called the Rh factor.

After air enters through the nose, it passes through the nasal cavity which filters, moistens, and warms it. Further filtering takes place in the pharynx, which also helps protect against infection, and then in the trachea which is just past the epiglottis, responsible for preventing food from entering the airway.

The columns of the Periodic Table are called groups and all elements in a group have the same number of electrons in their outer electron shell. The group that an element occupies generally determines its chemical properties as the number of outer shell electrons establishes the way it reacts with other elements to form molecules. So, because each element has the same number of electrons in its outer shell, each has similar reactivity.

In the mesosphere, temperature again drops as altitude increases until the coldest point in the Earth's atmosphere, the mesopause, is reached where temperatures fall to −225 °F (−143 °C).