The biosphere is the global ecological system integrating all living beings and their relationships. This includes their interactions with the lithosphere (the rigid outer part of the earth, consisting of the crust and upper mantle), hydrosphere (all surface water), and atmosphere (the envelope of gases surrounding the planet).

To provide oxygen to the body, blood flows through the heart in a path formed by the right atrium → right ventricle → lungs → left atrium → left ventricle → body. When blood enters the right side of the heart it is deoxygenated. It enters the left side of the heart oxygenated after traveling to the lungs.

A compound is a substance containing two or more different chemical elements bound together by a chemical bond. In covalent compounds, electrons are shared between atoms. In ionic compounds, one atom borrows an electron from another atom resulting in two ions (electrically charged atoms) of opposite polarities that then become bonded electrostatically.

The crust is the Earth's outermost layer and is divided into oceanic and continental types. Oceanic crust is 3 miles (5 km) to 6 miles (10 km) thick and is composed primarily of denser rock. Continental crust is 20 to 30 miles (30 to 50 km) thick and composed primarily of less dense rock. The crust makes up approximately one percent of the Earth's total volume.

The heart is the organ that drives the circulatory system. In humans, it consists of four chambers with two that collect blood called atria and two that pump blood called ventricles. The heart's valves prevent blood pumped out of the ventricles from flowing back into the heart.