The aorta is the body's largest artery and receives blood from the pulmonary vein via the left ventricle. From there, blood is circulated through the rest of the body through smaller arteries called arterioles that branch out from the heart. Finally, blood is delivered to bodily tissues through capillaries.

To provide oxygen to the body, blood flows through the heart in a path formed by the right atrium → right ventricle → lungs → left atrium → left ventricle → body. When blood enters the right side of the heart it is deoxygenated. It enters the left side of the heart oxygenated after traveling to the lungs.

Blood transfer is limited by the type and Rh factor of the blood. Someone who has Rh-factor negative blood cannot receive blood with a positive type but a person with Rh-factor positive type blood can receive Rh-negative blood. Type O negative blood is the universal donor because it can be given to a person with any blood type. Type AB positive is the universal recipient meaning someone with this blood type can receive any other type of blood.

If the ovum fails to become fertilized, the lining of the uterus sloughs off during menstruation. From puberty to menopause, this cycle of menstruation repeats monthly (except during pregnancy).

During intercourse, the penis ejaculates sperm, produced in the testes, into the vagina. Some of the sperm makes their way to the uterus where, if they encounter an egg to fertilize, unite with the ovum to form a fertilized egg or zygote. The zygote then may implant in the uterus and eventually develop into a fetus.