The biosphere is the global ecological system integrating all living beings and their relationships. This includes their interactions with the lithosphere (the rigid outer part of the earth, consisting of the crust and upper mantle), hydrosphere (all surface water), and atmosphere (the envelope of gases surrounding the planet).

If no oxygen is present, cellular respiration is anaerobic and will result in fermentation where either lactic acid or alcohol is used instead of oxygen.

Chemical waste like excess water, minerals, and salt are filtered from the blood by the kidneys and secreted into the urine. Urine is transported from the kidneys to the bladder through ureters.

The trachea branches into the left and right bronchi which each lead to a lung where the bronchi subdivide into smaller tubes called bronchioles. Each bronchiole ends in a small sac called an alveolus which allows oxygen from the air to enter the bloodstream via tiny blood vessels called capillaries.

Temperatures again increase with altitude in the thermosphere which is the hottest (4,530 °F / 2,500 °C) atmospheric layer due to direct exposure to the Sun's radiation. However, the gas in this layer is highly diluted so even though the atoms of gas may be very high in temperature, there are too few of them to effectively transfer much heat.