The aorta is the body's largest artery and receives blood from the pulmonary vein via the left ventricle. From there, blood is circulated through the rest of the body through smaller arteries called arterioles that branch out from the heart. Finally, blood is delivered to bodily tissues through capillaries.

Blood transfer is limited by the type and Rh factor of the blood. Someone who has Rh-factor negative blood cannot receive blood with a positive type but a person with Rh-factor positive type blood can receive Rh-negative blood. Type O negative blood is the universal donor because it can be given to a person with any blood type. Type AB positive is the universal recipient meaning someone with this blood type can receive any other type of blood.

The broadest classification of life splits all organisms into three groups called domains. The three domains of life are bacteria, archaea and eukaryota.

The heart is the organ that drives the circulatory system. In humans, it consists of four chambers with two that collect blood called atria and two that pump blood called ventricles. The heart's valves prevent blood pumped out of the ventricles from flowing back into the heart.

Mantle makes up 84% of the Earth's volume and has an average thickness of approximately 1,800 miles (2,900 km). It is dense, hot, and primarily solid although in places it behaves more like a viscous fluid as the plates of the upper mantle and crust gradually "float" along its circumference.