The biosphere is the global ecological system integrating all living beings and their relationships. This includes their interactions with the lithosphere (the rigid outer part of the earth, consisting of the crust and upper mantle), hydrosphere (all surface water), and atmosphere (the envelope of gases surrounding the planet).

The broadest classification of life splits all organisms into three groups called domains. The three domains of life are bacteria, archaea and eukaryota.

If no oxygen is present, cellular respiration is anaerobic and will result in fermentation where either lactic acid or alcohol is used instead of oxygen.

Mantle makes up 84% of the Earth's volume and has an average thickness of approximately 1,800 miles (2,900 km). It is dense, hot, and primarily solid although in places it behaves more like a viscous fluid as the plates of the upper mantle and crust gradually "float" along its circumference.

Food is mixed with gastric acid and pepsin in the stomach to help break down protein.