Blood transfer is limited by the type and Rh factor of the blood. Someone who has Rh-factor negative blood cannot receive blood with a positive type but a person with Rh-factor positive type blood can receive Rh-negative blood. Type O negative blood is the universal donor because it can be given to a person with any blood type. Type AB positive is the universal recipient meaning someone with this blood type can receive any other type of blood.

The heart is the organ that drives the circulatory system. In humans, it consists of four chambers with two that collect blood called atria and two that pump blood called ventricles. The heart's valves prevent blood pumped out of the ventricles from flowing back into the heart.

The large intestine (colon) follows the small intestine and processes the physical waste produced by digestion, absorbing water and minerials that remain back into the body. Solid waste is then stored in the rectum while liquid waste is stored in the bladder.

The spinal cord connects the brain to the body's network of nerves. It carries impulses between all organs and the brain and controls simple reflexes.

Temperatures again increase with altitude in the thermosphere which is the hottest (4,530 °F / 2,500 °C) atmospheric layer due to direct exposure to the Sun's radiation. However, the gas in this layer is highly diluted so even though the atoms of gas may be very high in temperature, there are too few of them to effectively transfer much heat.