apathetic
The definition for apathetic is "Showing little or no emotion." Used in a sentence: Carmine was concerned about his usually cheerful brother's apathetic attitude.
catastrophic
The definition for catastrophic is "Relating to extreme misfortune." Used in a sentence: The effects of the massive hurricane were catastrophic.
derelict
The definition for derelict is "Abandoned." Used in a sentence: The derelict house was condemned as a public hazard.
disconcert
The definition for disconcert is "To throw into confusion." Used in a sentence: Jennifer's outspoken criticism of the meal disoncerted the waiter.
futile
The definition for futile is "Without purpose, completely ineffective." Used in a sentence: Arguing with Andrew is futile because he never changes his mind.