catastrophic
The definition for catastrophic is "Relating to extreme misfortune." Used in a sentence: The effects of the massive hurricane were catastrophic.
negate
The definition for negate is "To make invalid." Used in a sentence: Paula negated Tiffany's argument by proving that her main premise was false.
pathos
The definition for pathos is "Sympathetic pity." Used in a sentence: The soldiers cherished the kindly Nurse Nightingale for her pathos.
turmoil
The definition for turmoil is "Extreme confusion, agitation." Used in a sentence: The windstorm caused such turmoil in the lake that the sailboat capsized.
turpitude
The definition for turpitude is "Essential baseness, depravity." Used in a sentence: The turpitude of the villain in the movie offended most audiences.