disdain
The definition for disdain is "Feeling of contempt." Used in a sentence: The arrogant writer did not hide his disdain for his uneducated dinner companion.
drub
The definition for drub is "To defeat decisively." Used in a sentence: The powerful young boxer drubbed the longtime champion.
inauspicious
The definition for inauspicious is "Not favorable." Used in a sentence: Gary believed the black foreboding sky was an inauspicious sign.
negate
The definition for negate is "To make invalid." Used in a sentence: Paula negated Tiffany's argument by proving that her main premise was false.
placebo
The definition for placebo is "An inactive substance used in medical testing." Used in a sentence: Tom, who had taken the placebo, found that his allergy symptoms did not go away.