The definition for diffident is "Lacking self–confidence." Used in a sentence: The diffident student never raised her hand in class, even when she knew the answer.

The definition for egotist is "Self–important person." Used in a sentence: Darren dreaded carpooling with the egotist Shelly, who talked about herself nonstop.

The definition for methodical is "Performed in an orderly manner." Used in a sentence: Oscar's methodical approach exasperated his free–spirited friend Ben.

The definition for negate is "To make invalid." Used in a sentence: Paula negated Tiffany's argument by proving that her main premise was false.

The definition for opportune is "Suitable or convenient." Used in a sentence: Quan stepped onto the platform at the most opportune time, just as the train pulled in.