flaw
The definition for flaw is "An imperfection." Used in a sentence: The otherwise perfect diamond had a tiny flaw that reduced its value.
futile
The definition for futile is "Without purpose, completely ineffective." Used in a sentence: Arguing with Andrew is futile because he never changes his mind.
gravity
The definition for gravity is "Importance, significance." Used in a sentence: Understanding the gravity of his error, Ken offered his humblest apology.
periodic
The definition for periodic is "Occurring at regular intervals." Used in a sentence: The periodic innterruptions of the cuckoo clock prevented Li from concentrating.
unscrupulous
The definition for unscrupulous is "Lacking principles." Used in a sentence: The unscrupulous salesman was fired for lying to his customers.