The definition for accessible is "Easy to reach or to approach." Used in a sentence: The introduction to the complex novel was, thankfully, written in clear accessible language.

The definition for buffoonery is "Foolish behavior." Used in a sentence: Clarence, an irrepressible comic, was held after cass for his buffoonery.

The definition for catastrophic is "Relating to extreme misfortune." Used in a sentence: The effects of the massive hurricane were catastrophic.

The definition for placebo is "An inactive substance used in medical testing." Used in a sentence: Tom, who had taken the placebo, found that his allergy symptoms did not go away.

The definition for preclude is "To rule out in advance." Used in a sentence: "Having cake now will preclude dessert later," said Amber's mother.