catastrophic
The definition for catastrophic is "Relating to extreme misfortune." Used in a sentence: The effects of the massive hurricane were catastrophic.
epitaph
The definition for epitaph is "Brief statement honoring a dead person." Used in a sentence: "Beloved by all,"" was the epitaph Edgar chose for his wife's tombstone.
implement
The definition for implement is "To carry out or accomplish." Used in a sentence: All Randolph needed to implement his plan was a moonless night and a long rope.
onset
The definition for onset is "Beginning." Used in a sentence: Crocuses bloom at the onset of spring, sometimes even before the snow melts.
placebo
The definition for placebo is "An inactive substance used in medical testing." Used in a sentence: Tom, who had taken the placebo, found that his allergy symptoms did not go away.