catastrophic
The definition for catastrophic is "Relating to extreme misfortune." Used in a sentence: The effects of the massive hurricane were catastrophic.
diffident
The definition for diffident is "Lacking self–confidence." Used in a sentence: The diffident student never raised her hand in class, even when she knew the answer.
genial
The definition for genial is "Sympathetic, friendly." Used in a sentence: The genial host warmly greeted his many guests.
melee
The definition for melee is "A tumultuous fight among several people." Used in a sentence: After the game, a melee broke out between fans of the opposing teams.
oblivious
The definition for oblivious is "Lacking awareness." Used in a sentence: Love–struck Charlie was oblivious to everyone but the object of his affection.