The definition for insolence is "Boldness or rudeness." Used in a sentence: The boy's insolence to the policeman embarrassed his mother.

The definition for methodical is "Performed in an orderly manner." Used in a sentence: Oscar's methodical approach exasperated his free–spirited friend Ben.

The definition for placebo is "An inactive substance used in medical testing." Used in a sentence: Tom, who had taken the placebo, found that his allergy symptoms did not go away.

The definition for preclude is "To rule out in advance." Used in a sentence: "Having cake now will preclude dessert later," said Amber's mother.

The definition for turmoil is "Extreme confusion, agitation." Used in a sentence: The windstorm caused such turmoil in the lake that the sailboat capsized.