disdain
The definition for disdain is "Feeling of contempt." Used in a sentence: The arrogant writer did not hide his disdain for his uneducated dinner companion.
onset
The definition for onset is "Beginning." Used in a sentence: Crocuses bloom at the onset of spring, sometimes even before the snow melts.
placebo
The definition for placebo is "An inactive substance used in medical testing." Used in a sentence: Tom, who had taken the placebo, found that his allergy symptoms did not go away.
refurbish
The definition for refurbish is "To brighten or freshen." Used in a sentence: Leeanne cleaned and mended all weekend to refurbish the shabby apartment.
straddle
The definition for straddle is "To favor opposing sides." Used in a sentence: Kia straddled the issue, not wanting to say whether James or Tara was right.