extant
The definition for extant is "Currently existing." Used in a sentence: Some consider Clint Eastwood the greatest extant American director.
grandiose
The definition for grandiose is "With an affectation of grandeur." Used in a sentence: The sweeping, grandiose staircase looked preposterous in the modest entry hall.
negate
The definition for negate is "To make invalid." Used in a sentence: Paula negated Tiffany's argument by proving that her main premise was false.
placebo
The definition for placebo is "An inactive substance used in medical testing." Used in a sentence: Tom, who had taken the placebo, found that his allergy symptoms did not go away.
preclude
The definition for preclude is "To rule out in advance." Used in a sentence: "Having cake now will preclude dessert later," said Amber's mother.