catastrophic
The definition for catastrophic is "Relating to extreme misfortune." Used in a sentence: The effects of the massive hurricane were catastrophic.
exasperation
The definition for exasperation is "The state of being irritated." Used in a sentence: The longer Jorge waited in line at the ticket counter, the more his exasperation grew.
extenuating
The definition for extenuating is "Partially excusing." Used in a sentence: The extenuating circumstance of Calvin's illness caused the teacher to excuse his lateness.
futile
The definition for futile is "Without purpose, completely ineffective." Used in a sentence: Arguing with Andrew is futile because he never changes his mind.
redouble
The definition for redouble is "To make twice as great." Used in a sentence: As the sun began to set, Brittany redoubled her effort to find the necklace she had dropped in the field.