catastrophic
The definition for catastrophic is "Relating to extreme misfortune." Used in a sentence: The effects of the massive hurricane were catastrophic.
demeanor
The definition for demeanor is "Behavior towards others." Used in a sentence: Carlos was well liked because of his charming demeanor.
diffident
The definition for diffident is "Lacking self–confidence." Used in a sentence: The diffident student never raised her hand in class, even when she knew the answer.
gruff
The definition for gruff is "Rough or stern in manner or speech." Used in a sentence: Heidi's grandfather was gruff, barking stern orders and hardly smiling.
placebo
The definition for placebo is "An inactive substance used in medical testing." Used in a sentence: Tom, who had taken the placebo, found that his allergy symptoms did not go away.