catastrophic
The definition for catastrophic is "Relating to extreme misfortune." Used in a sentence: The effects of the massive hurricane were catastrophic.
meticulous
The definition for meticulous is "Extrememly careful regarding details." Used in a sentence: The meticulous detective found every shred of evidence at the crime scene.
placebo
The definition for placebo is "An inactive substance used in medical testing." Used in a sentence: Tom, who had taken the placebo, found that his allergy symptoms did not go away.
rancorous
The definition for rancorous is "Marked by deep ill–will." Used in a sentence: The rancorous competition between the two chess clubs actually ended in a brawl.
solace
The definition for solace is "Source of consolation." Used in a sentence: Parents' weekend was a solace to Marjorie, whose beloved daughter had left for college.