gargantuan
The definition for gargantuan is "Gigantic." Used in a sentence: The gargantuan monster towered over the ten–story bulding.
gruff
The definition for gruff is "Rough or stern in manner or speech." Used in a sentence: Heidi's grandfather was gruff, barking stern orders and hardly smiling.
inflammatory
The definition for inflammatory is "Tending to excite anger." Used in a sentence: Garth's inflammatory remarks at the party made Gwen furious.
placebo
The definition for placebo is "An inactive substance used in medical testing." Used in a sentence: Tom, who had taken the placebo, found that his allergy symptoms did not go away.
preclude
The definition for preclude is "To rule out in advance." Used in a sentence: "Having cake now will preclude dessert later," said Amber's mother.