The definition for exasperation is "The state of being irritated." Used in a sentence: The longer Jorge waited in line at the ticket counter, the more his exasperation grew.

The definition for manifest is "Obvious." Used in a sentence: James finally made his affection manifest when he handed Jessica a red rose.

The definition for mediate is "To come between parties in order to reconcile." Used in a sentence: The diplomatic Henry was able to mediate between the quarreling sisters.

The definition for obnoxious is "Highly offensive." Used in a sentence: The manager asked the obnoxious diner to leave the restaurant.

The definition for preclude is "To rule out in advance." Used in a sentence: "Having cake now will preclude dessert later," said Amber's mother.