catastrophic
The definition for catastrophic is "Relating to extreme misfortune." Used in a sentence: The effects of the massive hurricane were catastrophic.
inauspicious
The definition for inauspicious is "Not favorable." Used in a sentence: Gary believed the black foreboding sky was an inauspicious sign.
meticulous
The definition for meticulous is "Extrememly careful regarding details." Used in a sentence: The meticulous detective found every shred of evidence at the crime scene.
negate
The definition for negate is "To make invalid." Used in a sentence: Paula negated Tiffany's argument by proving that her main premise was false.
turmoil
The definition for turmoil is "Extreme confusion, agitation." Used in a sentence: The windstorm caused such turmoil in the lake that the sailboat capsized.