catastrophic
The definition for catastrophic is "Relating to extreme misfortune." Used in a sentence: The effects of the massive hurricane were catastrophic.
elate
The definition for elate is "To fill with joy." Used in a sentence: It elated Margaret to be awarded first place in the science fair.
flaw
The definition for flaw is "An imperfection." Used in a sentence: The otherwise perfect diamond had a tiny flaw that reduced its value.
negate
The definition for negate is "To make invalid." Used in a sentence: Paula negated Tiffany's argument by proving that her main premise was false.
rail
The definition for rail is "To scold in harsh language." Used in a sentence: Clay began to cry as his irate manager railed at him for missing the deadline.