The definition for exasperation is "The state of being irritated." Used in a sentence: The longer Jorge waited in line at the ticket counter, the more his exasperation grew.

The definition for meticulous is "Extrememly careful regarding details." Used in a sentence: The meticulous detective found every shred of evidence at the crime scene.

The definition for negate is "To make invalid." Used in a sentence: Paula negated Tiffany's argument by proving that her main premise was false.

The definition for preclude is "To rule out in advance." Used in a sentence: "Having cake now will preclude dessert later," said Amber's mother.

The definition for rancorous is "Marked by deep ill–will." Used in a sentence: The rancorous competition between the two chess clubs actually ended in a brawl.