The definition for exasperation is "The state of being irritated." Used in a sentence: The longer Jorge waited in line at the ticket counter, the more his exasperation grew.

The definition for grandiose is "With an affectation of grandeur." Used in a sentence: The sweeping, grandiose staircase looked preposterous in the modest entry hall.

The definition for heinous is "Shockingly evil." Used in a sentence: Eduardo's heinous betrayal of Lydia shocked even Latasha, who knew his evil ways.

The definition for moderate is "Tending toward the average." Used in a sentence: The best–selling writer was disappointed; his new novel was only a moderate success.

The definition for placebo is "An inactive substance used in medical testing." Used in a sentence: Tom, who had taken the placebo, found that his allergy symptoms did not go away.