The definition for diffident is "Lacking self–confidence." Used in a sentence: The diffident student never raised her hand in class, even when she knew the answer.

The definition for flaw is "An imperfection." Used in a sentence: The otherwise perfect diamond had a tiny flaw that reduced its value.

The definition for futile is "Without purpose, completely ineffective." Used in a sentence: Arguing with Andrew is futile because he never changes his mind.

The definition for mediate is "To come between parties in order to reconcile." Used in a sentence: The diplomatic Henry was able to mediate between the quarreling sisters.

The definition for negate is "To make invalid." Used in a sentence: Paula negated Tiffany's argument by proving that her main premise was false.